Session 4: Building Management System Best Practices in GMP Facility
3:00 PM – 3:45 PM | East Red Level, Suite 10
Building Management Systems (BMS) are generally overlooked in the grand scheme of constructing a GMP Facility, with other automated systems in the building getting the majority of attention. Nevertheless, a building management system is mainly responsible for maintaining pressurization and temperature conditions within GMP areas as well as the operation of the overall facility. When a drug manufacturer can quickly bring a product to market, they can reach more patients and effect their lives much more quickly. When they do that by delivering a new facility on time and on budget, it can be life-changing for many. The panel will discuss how to best design, install, and commission a building management system in a complex GMP facility so that a drug manufacturer can bring products to market more quickly. Drawing on success stories and case studies from the field, the panel will provide best practices to consider when building a new GMP facility. System Design: discussion about the important aspects of the BAS system design and what to think about before construction begins. Team Selection: a conversation on best practices for selecting members of the construction and subcontractor teams. Project Delivery: best practices from start to finish (engineering, installation, and commissioning) that help define the success of a project.
Milton Chan, Engineering and Quality Manager, Albireo Energy Aaron Conant, Senior Director, Engineering and Capital Projects, Alnylam Mike Denietolis, Project Engineer, Albireo Energy Mike Good, BMS Commissioning Specialist, CAI John Kelliher, Associate Director, Plant Engineering, Alnylam Jason Theberge, Vice President, Commodore Builders
Moderator: Dave Gallagher, Account Manager, Albireo Energy
Milton Chan is an engineering manager at Albireo Energy, where he is responsible for project engineering estimating, scope development, and fundamental design for turnkey projects. He manages the team that works on hardware and software design submittals, installation drawings, engineering documentation, sequence of operations, and graphics design. He has been with an Albireo company for nearly a decade, and previously worked in the biotech industry at Sanofi Genzyme.
Aaron Conant leads the Engineering and Capital Projects departments at Alnylam Pharmaceuticals. After graduating from the University of Maine with a bachelor’s in chemical engineering, he spent the first 10 years of his career in the Pulp and Paper industry before transitioning to Biotech for the past 21 years, working for Biogen, Amgen and now Alnylam. He has been part of many fast-paced projects from system renovation to greenfield installations in the Automation space, across GMP and non-GMP facilities.
Mike Denietolis has dedicated himself to a meaningful career in engineering, beginning with two years of apprenticeship at a Utility Engineering firm. He then became an electrical foreman and shortly thereafter began working in the security and low voltage fields, showing immense skill in creating control schemes for door interlocks and trouble shooting wiring for Residential HVAC applications. With his wealth of knowledge, Mike then rose to the challenge of becoming a lead installer at Guardian EMS, successfully installing systems for BCM, AEM, Automated Logic and Huntington Controls. Now, as a Project Engineer at Albireo Energy, Mike works towards utilizing his experience to deliver solutions to issues hindering project completion.
Dave Gallagher is an account executive at Albireo Energy, where he is responsible for sales, business development and key account management of Albireo pharmaceutical clientele. Over the past 13 years Dave has help to build Albireo’s portfolio of key clientele consisting of Alnylam, Moderna, Bristol Myers Squibb, and many other large clients in the region. He also works closely with our internal team of engineers and project managers to meet and exceed customer expectations. Dave has a B.S. in Mechanical Engineering from the University of New Hampshire.
Mike Good has 30 years of Industry BAS experience and 12 years performing Commissioning Services. From BAS application design and sales to Project Management and Energy Solutions commissioning, he has developed and applied a broad range of experiences in all aspects of the industry. Currently Mike leads the Building Commissioning efforts for CAI in the Northeast, and provides SME support for US and global client locations as well. Recently on behalf of his clients, Mike has developed and executed Design Development specifications for various BAS manufacturers, has designed BAS architecture and Gas Detection systems and has led vendor RFP and selection programs for clients. He is also engaged in Program Management for MEP and BAS workstream oversight in biotech spaces.
John Kelliher has over 25 years of experience in both Plant Engineering and Facilities Management Roles within the Biotechnology Industry. At Alnylam, John and the team manage all aspects of the core utility systems, infrastructure, and energy management for Alnylam’s Manufacturing, Laboratory and Office Space in the US. Prior to Alnylam Pharmaceuticals, John held increasingly responsible senior Plant Engineering and Facilities Management Roles at Biogen supporting their Cambridge Site for nearly 19 years. Before Biogen, John was the Plant Engineer for Creative Biomolecules / Stryker Biotech in Hopkinton, MA. John has a B.S. in Chemical Engineering from Northeastern University.
Jason Theberge, Vice President / Life Science Group Leader at leading construction management firm Commodore Builders, has 28 years of experience managing complex, technical projects. Over the course of his career, he has served some of the top life science companies in the country, including Biogen, Bristol-Myers Squibb, Takeda, Crispr, and Rentschler. Jason’s immense knowledge of research and development, cGMP manufacturing, supply chain facilities, and operations provides clients with a unique and valuable perspective during design, construction, commissioning, and validation. His experience includes buildouts of specialized laboratories, cGMP manufacturing, warehouses, and packaging/labeling facilities. His signature project was the “first-ever” ground-up commercial cGMP manufacturing facility that incorporated extensive single-use technology.